Plasticity of GABA transporters: an unconventional route to shape inhibitory synaptic transmission
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چکیده
منابع مشابه
Plasticity of GABA transporters: an unconventional route to shape inhibitory synaptic transmission
The brain relies on GABAergic neurons to control the ongoing activity of neuronal networks. GABAergic neurons control the firing pattern of excitatory cells, the temporal structure of membrane potential oscillations and the time window for integration of synaptic inputs. These actions require a fine control of the timing of GABA receptor activation which, in turn, depends on the precise timing ...
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GABA transporters belong to a large family of neurotransmitter:sodium symporters. They are widely expressed throughout the brain, with different levels of expression in different brain regions. GABA transporters are present in neurons and in astrocytes and their activity is crucial to regulate the extracellular concentration of GABA under basal conditions and during ongoing synaptic events. Num...
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ژورنال
عنوان ژورنال: Frontiers in Cellular Neuroscience
سال: 2014
ISSN: 1662-5102
DOI: 10.3389/fncel.2014.00128